alpha Karyopherins

《英文msh词典》alpha Karyopherins
[主题词] alpha Karyopherins
[入口词] Importin-alpha
[入口词] Karyopherin alpha
[入口词] NLS Receptor
[入口词] NLS-Binding Protein
[入口词] NLSBP
[入口词] Nuclear Localization Sequence Receptor
[入口词] Nuclear Localization Signal-Binding Protein
[入口词] Karyopherins,alpha
[入口词] receptor,NLS
[中文释义] α核胞浆转运蛋白类
[英文释义] Nucleocytoplasmic transport molecules that bind to the NUCLEAR LOCALIZATION SIGNAL of cytoplasmic molecules destined to be imported into the CELL NUCLEUS. Once attached to their cargo they bind to BETA KARYOPHERINS and are transported through the NUCLEAR PORE COMPLEX. Inside the CELL NUCLEUS alpha karyopherins dissociate from beta karypherins and their cargo. They then form a complex with CELLULAR APOPTOSIS SUCCEPTIBILITY PROTEIN and RAN GTP-BINDING PROTEIN which is exported to the CYTOPLASM.